3M DuraPrep Surgical Solution

The 3M DuraPrep Surgical Solution uses a potent, dual-action formula combining two high-efficacy antimicrobial agents to ensure superior, long-lasting protection. The active ingredients are:

• Iodine Povacrylex (0.7% available iodine)
• Isopropyl Alcohol (74% w/w)

This robust formulation is designed for persistent bacterial kill, maintaining low resident bacterial counts for at least 48 hours following a challenge with blood or saline, and effective protection against transient bacteria for at least 12 hours. This solution is clinically proven and meets both AORN and CDC guidelines for reducing surgical site infections.

Yes, the 3M DuraPrep Surgical Solution provides persistent and effective antimicrobial protection through a single painted coat application.

The long-lasting efficacy is confirmed by clinical data:

• Resident Bacteria: Maintains low bacterial counts for at least 48 hours following blood and saline challenge.
• Transient Bacteria: Keeps bacterial counts low for at least 12 hours.

This sustained action is achieved because the solution dries quickly to a water-insoluble film. This durable film not only secures immobilized bacteria, reducing the risk of migration, but also significantly enhances surgical drape adhesion, resisting removal from irrigation or bodily fluids during the procedure. The active formulation consists of Iodine Povacrylex (0.7% available iodine) and Isopropyl Alcohol (74% w/w).

Yes, the 3M DuraPrep Surgical Solution is latex-free, making it suitable for patients with latex sensitivities.

Yes, the 3M DuraPrep Surgical Solution is uniquely designed for a streamlined, single-coat application that eliminates the need for scrubbing. This is the only surgical prep approved by the FDA NDA for this method.

This application method simplifies preoperative routines while ensuring high-level, persistent antimicrobial protection:

• Long-Lasting Efficacy: Maintains low resident bacterial counts for at least 48 hours and protects against transient bacteria for at least 12 hours, even after blood/saline challenges.
• Protective Film: Dries quickly to a water-insoluble film that immobilizes bacteria, minimizing the risk of microbial migration to the incision site.
• Drape Adhesion: The film significantly improves the adhesion of surgical drapes and resists removal from irrigation or bodily fluids.
• Compliance: The prep meets established AORN and CDC guidelines for reducing Surgical Site Infections (SSIs).

No, scrubbing is not required when using the 3M DuraPrep Surgical Solution. This solution is specifically designed for a single, painted coat application, which streamlines the preoperative process and saves valuable time.

Yes, the 3M DuraPrep Surgical Solution is engineered to deliver highly effective and persistent antimicrobial protection through its single coat application:

• Resident Bacteria: Maintains low bacterial counts for at least 48 hours following blood and saline challenge.
• Transient Bacteria: Provides protection for a minimum of 12 hours.

This long-lasting efficacy is supported by its dual-active formulation and unique drying property:

1. Active Ingredients: The solution contains Iodine Povacrylex (0.7% available iodine) and Isopropyl Alcohol (74% w/w) for rapid and sustained antimicrobial action.
2. Protective Film: It dries to a durable, water-insoluble film. This film acts as a primer, physically immobilizing any non-killed bacteria and significantly reducing the risk of microbial migration toward the surgical site. The film is designed to resist removal by irrigation fluids, sponging, or bodily fluids throughout the procedure.

The 3M DuraPrep Surgical Solution is available in two applicator sizes, both featuring the same single-coat, no-scrub formula for persistent antimicrobial protection. The size required is based on the necessary coverage area for the surgical site.

Here are the recommended applications, including the typical coverage area for each variant:

Yes, the 3M DuraPrep Surgical Solution is clinically proven to meet both AORN (Association of periOperative Registered Nurses) and CDC (Centers for Disease Control and Prevention) guidelines for reducing surgical site infections (SSIs).

This compliance is ensured by its unique formulation and features:

• Long-Lasting Antimicrobial Persistence: It maintains low resident bacterial counts for at least 48 hours (even after blood and saline challenges) and at least 12 hours against transient bacteria.
• Bacteria Immobilization: The solution dries quickly to form a water-insoluble primer film that traps unkilled bacteria, minimizing their migration toward the incision site, even without an incise drape.
• Efficient, Single-Coat Application: It is FDA approved for application in a single painted coat, eliminating the need for scrubbing, which supports efficient surgical preparation protocols.
• Superior Adhesion: The solution enhances drape adhesion and resists removal by surgical fluids and contact.

The DuraPrep film is designed to be left on the skin after surgery, where it will gradually wear away naturally over time. However, if immediate removal is necessary, the water-insoluble film must be dissolved using a specialized product. You should use 3M Remover Lotion (available under product numbers #8610 or #8611) for this purpose, as it is specifically formulated to break down this durable film.

The 6 mL applicator of 3M DuraPrep Surgical Solution covers approximately 80 square inches (8” x 10”).